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Cancer Sci (2009) 100(5):9707

From these molar concentrations the status of the GSSG/2GSH couple was calculated using the Nernst equation E h c = 255 30 log ([GSH] 2 / [GSSG]) in mV [26], assuming an intracellular pH of 7.25 for RBCs and a temperature in vivo of 37 C [27]

Cosmelan peels are used in conjunction with a specific at-home treatment protocol that patients need to follow to augment the in-office Cosmelan peel

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For RCTs, this included assessment of: (1) risk of bias (via Cochrane RoB 2 tool), (2) inconsistency of results across studies, (3) indirectness of evidence, (4) imprecision due to sample size or confidence intervals, and (5) potential publication bias